It is generally not recommended to smoke with grillz in your mouth. According to dentist, the heat and chemicals from smoking can cause damage to the grillz and even harm your teeth and gums. Smoking can discolor or warp the grillz, and the high heat can also cause the metals to leach into your mouth, which can be harmful. Therefore, if you wear grillz and smoke, it is recommended that you remove them before smoking to protect your health and the condition of your grillz.